Revefenacin Impurity 16 HCl CAS 886508-20-9(Free Base)
| CAS No. | 886508-20-9(Free Base) |
| Molecular Formula | C12H21N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Revefenacin Impurity 16 HCl (CAS 886508-20-9(Free Base), C12H21N3O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Revefenacin Impurity 16 HCl (C12H21N3O2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H21N3O2 HCl |
| Molecular Weight | 275.78 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Revefenacin Standards
- Revefenacin impurity 83 (CAS 102-18-1)
- Revefenacin Impurity 26 (CAS 108015-71-0)
- Revefenacin Impurity 26 HCl (CAS 108015-71-0(free base))
- Revefenacin Impurity N2 (CAS 115293-14-6)
- Revefenacin impurity 103 (CAS 1155168-91-4)
- Revefenacin Impurity N12 (CAS 1158699-78-5)
- Revefenacin Impurity 52 (CAS 1158699-78-5(free base))
- Revefenacin Impurity 39 (CAS 1284980-54-6)
Recommended Standards
- Aztreonam Impurity 51 (CAS CATO-C4X-152251)
- Nebivolol Impurity 44 (CAS 197706-51-7)
- Brexpiprazole Impurity 119 (CAS CATO-C4X-1131119)
- Methyl 6-Bromo-5-methylnicotinate (CAS 1210451-92-5)
- ethyl 2-oxo-2-(5,6,7,8-tetrahydronaphthalen-2-yl)acetate (CAS 5803-71-4)
- 6-Chloro-[3,4'-bipyridine]-4-carbaldehyde (CAS 1227583-01-8)
- 6-Bromo-2-(difluoromethyl)nicotinic acid (CAS 1211536-36-5)
- 4-Chloro-2-fluoro-3-(3-methylphenyl)propiophenone (CAS 898791-20-3)
- 2-Amino-4-methoxybenzene-1-sulfonamide (CAS 72106-13-9)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com